SUBMIT YOUR MANUSCRIPT
By Shehnila Javed, Zaheer Udin Babar
ABSTRACT Brucellosis is a multisystem disease often caused by occupational exposure to animals or animal products. Hepatic involvement is not rare given the affinity of Brucella for the reticuloendothelial system but hepatic brucelloma, a necrotising inflammation of hepatocytes leading to formation...
By Shahzad Akhtar, Syed Mukarram Hussain, Hafsa Niaz, Tariq Mukhtar Farani, Asif Abbasi
ABSTRACT Chilaiditi sign is a rare radiological finding often discovered incidentally on chest or abdominal x-rays when there is hepato-diaphragmatic interpositioning of small or large intestines. Usually asymptomatic but when accompanied by cardiac, respiratory or abdominal symptoms, it is known as...
By Syed Qasim Hashmi, Saad Irfan, Anas Hashim, Hasham Ali
ABSTRACT Branchial cleft anomalies are uncommon in adults but common in children. Bilateral presentations are very rare especially bilateral cleft fistulae and sinuses simultaneously and mostly are a component of familial syndromes like branchio-oto-renal syndrome (BORS). We present a case of a 20-y...
By Mustajab Alam, Muhammad Zain Arshad, Muhammad Hussain, Muhammad Aftab Hassan, Maryam Bibi
ABSTRACT Colonic lithobezoars, an uncommon subset of gastrointestinal foreign body impactions characterised by the accumulation of indigestible materials within the colon, typically present with symptoms of obstruction but are rarely reported in the medical literature. Diagnostic imaging modalities,...
By Ufaq Rao, Muhammad Adil Asim
ABSTRACT Radicular cysts are the prevailing inflammatory jaw cysts. Historical surgical modalities, including marsupialization and enucleation, have been conventionally employed to optimise postoperative conditions and expedite the healing trajectory in the affected regions. The fundamental su...
By Sarah Akram, Rabia Arshad, Chaudhry Usman Ahmed, Hamza Naeem
ABSTRACT An under-studied occurrence, systemic inflammatory polyarticular gout syndrome (SIPGS), represents an acute flare of polyarticular gout with raised inflammatory markers in the absence of any source of infection. It is most commonly precipitated by advanced age, male gender, chronic poorly-t...
By Safa Taflan, Esin Kurtulus Ozturk, Saffet Ozturk, Saadet Demirtas inci
ABSTRACT Cardiac metastasis from lung cancer as the first presentation is a relatively rare phenomenon and has a poor prognosis. Lung cancers can cause myocardial involvement through direct invasion, hematogeneous spread or lymphatic spread. Contrary to popular belief, cardiac metastases are not unc...
By Serhan Yilmaz, Cenk Ozkan, Hakan Bolukbasi, Osman Sibic
ABSTRACT Anatomical variations of biliary and vascular structures may affect the safe performance of cholecystectomy during a surgery. A 58-year female patient was admitted to the emergency department with a complaint of right upper quadrant pain and was diagnosed with cholelithiasis and acute chola...
By Yu Ren, Tian-long He, Dan-dan Zhou, Cheng-wei Lu
ABSTRACT Hordeolum is an acute, painful, and common eyelid disease with high prevalence. Studies have illustrated that intense pulsed light (IPL) is an effective and feasible option for meibomian gland dysfunction (MGD)-related dry eye disease (DED) and other eyelid diseases. This is the first study...
By Mehmet Gunhan Tekin, Nurgul Ozgur Yurttas
ABSTRACT Midostaurin is a FMS-like tyrosine kinase 3 (FLT3) inhibitor used in FLT3-positive acute myeloid leukaemia (AML). Midostaurin has been rarely associated with Sweet’s syndrome. We present a case of a female who developed Sweet’s syndrome due to midostaurin. After skin biopsy was ...
By Suha Kaaki, Alaa Altowaijeri, Sami Alnassar, Waseem M. Hajjar
ABSTRACT Pulmonary sequestration is a rare congenital anomaly of the lung. It presents as an area of dysplastic and non-functional pulmonary tissue, with aberrant blood supply and multiple pathways of venous drainage. It usually presents in the left lung and is supplied by a single branch from the ...
By Sona Duwal, Zainab Nazir Sangi, Sohail Ahmed Khan
ABSTRACT An osteoid osteoma is a small non-malignant osteoblastic tumour with characteristic radiological finding of central lucent nidus with surrounding sclerosis typically presenting as non-traumatic night pain relieved by taking Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). Atypical cases...
By Zain Muhammad, Muhammad Naveed, Muhammad Usama, Rizwan Akram
ABSTRACT Disc herniation of lumbar spine is common but it rarely presents at the intradural location. As for any disc herniation, patient undergoes the same clinical and radiologic examinations. However, the surgical excision is way more challenging. To remove the intradural disc material, a formal ...
By Miao Wen, Xue Meng, Yitian Long, Zhi Yang, Bing Fu
ABSTRACT Early administration of adjuvant chemotherapy for tumour patients has a positive impact on patients’ quality of survival and may improve long-term outcomes. However, chemotherapy also results in a variety of side-effects, of which cardiotoxicity is the most serious complication. We re...
ABSTRACT Nutcracker syndrome (NCS) is a rare disease caused by obstruction of renal venous reflux, leading to increased kidney pressure and proteinuria. Diagnosis is based on specific criteria and confirmed through left renal vein colour Doppler ultrasound. Adolescents with a thin body, showing neph...
By Muhammad Nasir, Ilyas Sadiq, Menahil Farooq Cheema, Ramsha Zafar Khan, Haseeb Mehmood Qadri
ABSTRACT Uretero-iliac artery fistula (UIAF) is a rare condition which offers a significant diagnostic challenge due to its overlapping clinical picture with other renal and urinary pathologies. We report a case of a 72-year male who presented with gross haem...
By Shahid Pervaiz, Ahmed Uzair, Nauman Ijaz Bhatti, Zoha Toor, Muhammad Sajawal
ABSTRACT Silicosis, one of the uncommon occupation-related lung diseases in Pakistan, is caused by long-term inhalation of crystalline silica particles. Progressive massive fibrosis (PMF) is a severe, not routinely encountered adverse outcome of silicosis, characterised by mass-like fibrotic opaciti...
By Teyyeb Azeem Janjua, Muqaddas Noor, Aisha Fawad
ABSTRACT Epithelial inclusion cysts of the conjunctiva are thin-walled, nonkeratinised epithelium-lined, benign cystic lesions. These sac-like lesions are filled with clear serous fluid with shed epithelial cells or gelatinous mucous substance. They are slowly progressive and cause cosmetic disfigur...
By Nauman Zafar, Nadeem Bin Nusrat, Assad Ur Rehman, Shujah Muhammad, Saira Imtiaz
ABSTRACT Renal Malignant Epithelioid Angiomyolipoma (RMEAML) is a rare subtype of angiomyolipoma (AML) with malignant potential. We present two case reports of a 20-year boy and a 46-year female who were diagnosed with RMEAML after presenting with flank pain and haematuria at our institution in the ...