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VOLUME 3, YEAR 2025

Aims & Scope

JCPSP Case Reports is a peer-reviewed online-only journal by the College of Physicians and Surgeons Pakistan (CPSP). The journal publishes original case reports in all fields of Medical Sciences. The purpose of JCPSP Case Reports is to provide clinicians and researchers, in particular postgraduate trainees and fellows of CPSP, a forum to publish their unique experiences to a wide readership for the advancement of clinical acumen.

Latest Articles
Volume 3 | Year 2025
Looking Ahead – A New Year of Growth and Innovation for JCPSP Case Reports

By Muhammad Shoaib Shafi

Page #: 1-1


Sarcomatoid Variant of Renal Cell Carcinoma and a Comprehensive Exploration of Its Molecular Pathogenesis

By Hamza Bashir, Harris Hassan Qureshi, Muhammed Mubarak, Muhammad Nauman, Syed Muhammad Faiq

Page #: 252-255

ABSTRACT Renal cell carcinoma (RCC) is a common neoplasm of the kidney. A rare, highly aggressive form of RCC that can arise in any subtype of this disease is the sarcomatoid type. RCC with sarcomatoid differentiation (sRCC) has a high likelihood of metastasising and, thus, shows a poor prognosis. S...


Pseudohypobicarbonataemia Unmasking Multiple Myeloma in a Young Female: An Unusual Presentation

By Anam Haider, Hameedullah Tareen

Page #: 256-258

ABSTRACT The authors present a case of a patient whose blood bicarbonate (HCO3) levels were extremely low, ranging from 5.4 to 7.9 mEq/L. In clinical chemistry, paraproteins’ interference in tests is not unheard of, but is still quite uncommon. Here, we report a case of multiple myeloma in whi...


Papillary Thyroid Carcinoma Presenting as a Parotid Gland Swelling: A Silent Recurrence

By Uzair Luqman, Zainab Sohail Raja, Maryam Nazir Kiani, Amber Kiyani, Hania Noor

Page #: 262-265

ABSTRACT Papillary thyroid carcinoma (PTC) is one of the most common forms of thyroid cancer, originating from the follicular cells of the thyroid gland. It accounts for approximately 80–85% of all thyroid malignancies and is prevalent in women, with a higher incidence in middle-aged adults. T...


Perioperative Management and Anaesthetic Considerations in Vagal Nerve Stimulators’ Implantation in Refractory Epilepsy: First Case Series from Pakistan

By Fahad Tariq, Syed Tashfain Bin Zafar, Hameed Ullah

Page #: 266-269

ABSTRACT This case series reports the first-ever successful implantation of vagal nerve stimulators (VNS) for refractory epilepsy in this region. It details the anaesthetic management of two patients who underwent VNS implantation, both of whom achieved positive outcomes with stable postoperative re...


Comprehensive Treatment of a Rare Primary Mediastinal Yolk SAC Tumour with Immature Teratoma

By Ma Dengyun, Huang Hanqing

Page #: 272-274

ABSTRACT Primary anterior mediastinal yolk SAC tumours are rare but fatal, and primary mediastinal endodermal sinus tumours with immature teratomas are even rarer. This article reports a 31-year man with a yolk SAC tumour with an immature teratoma who was admitted to the hospital for repeated chest ...


Gastric Perforation: A Case Report of an Unusual Complication of Rib Fracture due to Blunt Abdominal Trauma

By Tariq Abdullah, Tayyaba Shahzad, Frogh Elahi, Rida Noor

Page #: 275-278

ABSTRACT Blunt abdominal trauma is far more common than penetrating injuries, but gastric perforation is more frequently associated with penetrating abdominal trauma. Rib fractures due to blunt trauma usually cause solid organ injury. Blunt gastric perforations are rare, accounting for <2% of all...


Robot-Assisted Augmentation Ileocystoplasty (AIC) for Genitourinary Tuberculosis Using a New Robot Platform

By Rehan Mohsin, Haris Jameel, Haris Qureshi, Gohar Sultan, Hamza Ather

Page #: 279-282

ABSTRACT Genitourinary tuberculosis (GUTB) can lead to a severely contracted bladder, often necessitating augmentation ileocystoplasty (AIC) for reconstruction. Robot-assisted laparoscopic techniques offer several potential advantages over open surgery, including enhanced visualisation and improved ...


Two Cases of Tension Pneumocephalus after Endonasal Skull Base Surgery and Vestibular Schwannoma Surgery

By Yiru Wang, Xia Shen

Page #: 283-285

ABSTRACT Pneumocephalus, the presence of air in the cranial cavity, is a rare but serious complication of both head trauma and post-neurosurgery procedures. Tension pneumocephalus, marked by significant air accumulation causing mass effect and neurological symptoms, is even more uncommon and demands...


Post-Biperiden Myocardial Depression and Acute Pulmonary Oedema: A Case Report

By Okkes Zortuk, Didem Kilic

Page #: 286-288

ABSTRACT Biperiden, a muscarinic receptor antagonist, is utilised in antipsychotic therapies and has been associated with a restricted incidence of cardiac side effects. This case study details a 30-year male patient who had acute pulmonary oedema and cardiac depression after a biperiden overdose. T...


Primary Paraganglioma of the Lung: A Case Report

By DengJun Huang, Ruizhi Wu, Jun Nie

Page #: 289-291

ABSTRACT Primary pulmonary paraganglioma, a rare type of tumour, is infrequently observed in clinical practice. The clinical data of a case of primary pulmonary paraganglioma admitted to the Department of Thoracic and Cardiac Surgery of the Hospital were analysed, and the diagnosis and treatment of ...


Ultrasound Features of Merkel Cell Carcinoma in the Right Upper Arm: A Case Report

By Zishu Yang, Xingzi Li, Boyuan Xing

Page #: 292-294

ABSTRACT Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine skin cancer, often presenting with nonspecific clinical features. Early diagnosis is crucial for optimal management. This case report details the ultrasound (US) findings in an 80-year old female with a right upper arm MCC....


POLE-Mutated Molecular Subtype of Endometrioid Carcinoma: An Aggressive Pilomatrix-Like Neoplasm with Diffusely Aberrant ß-Catenin Expression

By Dan Ye, Xiaowei Qi, Yankui Liu, Yan Qin, Zhenwei Wang

Page #: 295-298

ABSTRACT Endometrioid adenocarcinoma with pilomatrix carcinoma-like morphology represents a recently reported high-grade endometrial carcinoma subtype, frequently harbouring the CTNNB1 gene mutations and demonstrating highly aggressive biological behaviour. However, the present case differs from pri...


Vitreous Occlusion of Ahmed Glaucoma Tube in a Patient with Aphakic Glaucoma - A Case Report

By Hina Qazi, Haroon Tayyab, Pir Salim Mahar

Page #: 299-302

ABSTRACT This report presents an infrequent but well‑recognised case of delayed Ahmed glaucoma valve tube obstruction caused by a vitreous plug in the anterior chamber of a 51-year Pakistani male with aphakic secondary open‑angle glaucoma. The obstruction was successfully managed through an ante...


Medical Management of Glaucoma Secondary to Idiopathic Elevated Episcleral Venous Pressure

By Aleena Shah, Ayisha Kausar

Page #: 303-305

ABSTRACT Idiopathic elevated episcleral venous pressure (IEEVP) is a rare cause of secondary open-angle glaucoma. The authors report a case of a 36-year male who presented with dilated episcleral vessels in the right eye. Gonioscopy revealed bilateral open angles with blood in Schlemm’s canal ...


A Journey from Renal Cell Carcinoma to Intestinal Metastasis: A Case Report

By Mahnoor Asim, Asad Ullah Khan, Syed Irfan Kabir, Muhammad Waqas

Page #: 306-307

ABSTRACT Renal cell carcinoma (RCC) is one of the most common primary renal cancers. Its metastasis to the duodenum is a rare occurrence. Commonly reported symptoms are bleeding, anaemia, and flank pain. This report discusses a case of a 74-year old male with no known comorbidities, who was diagnose...


Delayed Presentation of Traumatic Diaphragmatic Hernia Complicated by Gangrene: A Case Report and Review of Literature

By Hunain Muhammad Asif, Tasneem Shabbir Siamwala, Akram Rajput, Farhat Jaleel

Page #: 308-310

ABSTRACT Blunt trauma to the abdomen can lead to various injuries, including diaphragmatic ruptures. Late presentation of traumatic diaphragmatic hernia is unlikely and can cause abdominal visceral perforation or gangrene. A young female presented to the emergency department with a history of blunt ...


Delayed IPEX Syndrome with a Rare Mutation

By Wen-Ting Xu, Tao Fan, Shi-Fang Zheng, Ya-Zhou Xiao

Page #: 311-313

ABSTRACT Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is a rare, life-threatening X-linked recessive disorder caused by FOXP3 gene mutations, with an incidence of less than one in a million. It typically presents in infancy, with half of the cases manifesting withi...


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