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By Aun Ali, Ammara Salam, Madeeha Shahid, Pirhay Fatma, Muhammad Ahmed
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ABSTRACT Caroli’s disease is a congenital disorder characterised by irregular saccular dilatation of the intrahepatic biliary tree on imaging. Rarely, it has been associated with autosomal recessive polycystic kidney disease (ARPKD) due to a mutation in the PKHD 1-gene. We present a case of a ...
By Ravi Kumar, Farzan Shamshad, Jawahar Lal
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ABSTRACT Metronidazole, a nitroimidazole compound, is a frequently utilised antimicrobial medication employed in the management of a wide range of bacterial and protozoal infections. Metronidazole can rarely cause neurological side effects such as encephalopathy, cerebellar dysfunction, and peripher...
By Muhammad Saeed, Mahnoor Saeed, Mohammad Al-Sumaili, Saeed Al-Tala, Badriah Gharamah Al-Asmari
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ABSTRACT Poretti-boltshauser syndrome (PBS) is a rare autosomal recessive (AR) disorder that occurs due to a mutation in the LAMA1 gene. Clinically and radiologically, PBS is described as a disorder associated with ophthalmological problems, developmental delay, cerebellar dysplasia, cerebellar cyst...
By Badriah G. Alasmari, Ibrahim Yagoub, Mohaned Mustafa, Saeed Altala, Samah Alfadel
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ABSTRACT Children with 22q11.2 deletion syndrome (22q11DS), also known as DiGeorge syndrome (DGS), experience an array of symptoms, including heart, skeletal, and immune system problems and developmental delays. 22q11DS is a common genetic disease characterised by broad phenotypic variability. Few s...
By Qazi Syed Irfanullah Shah, Akebaier Sulaiman, Xuefeng Wan, Lv Jin, Palida Abulizi
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ABSTRACT This case report describes a 62-year woman with vulvar malignant melanoma and concurrent chronic hepatitis B infection. Vulvar melanoma is a rare and aggressive cancer, accounting for less than 5% of all melanoma cases. The patient initially presented with a firm, painless vulvar lesion, wh...
By Faiqa Binte Aamir, Shanila Ahmed, Qurratulain Chundriger, Imran Ahmad
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ABSTRACT Basal cell carcinoma (BCC) develops commonly in body areas that are exposed to sunlight, such as the face and neck. It is uncommon in the closed areas of the body and quite rare in the perianal and genital regions. We are reporting an extremely rare case of a middle-aged man with BCC of the...
By Anum Anwar
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ABSTRACT Peripartum cardiomyopathy (PPCM) is a rare but serious condition characterised by heart failure during late pregnancy or early postpartum. This report discusses two cases of PPCM in young parturients highlighting variable presentations and outcomes. Case one involved a 26-year woman who det...
By Maira Aslam, Mariam Shah, Sana Sayeed, Aroosa Kanwal
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ABSTRACT Neuro-endocrine tumours (NETs) arise from neuro-endocrine cells and can potentially occur in any part of the body, the most common site being the gastrointestinal (GI) tract. GI stromal tumours (GISTs) arise from pacemaker cells and are also considered as common GI tumours. However, the syn...
By Xinyuan Teng, Ligui Jin, Lin Feng, Guoliang Dai, Jiayu Shen
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ABSTRACT Amniotic band syndrome (ABS) is defined as fibrous strands entangling foetal parts, resulting in malformation, deformation, disruption, or even foetal demise. Early diagnosis is necessary for timely intervention and to lower undesirable pregnancy-related events. We report a 28-year pregnant...
By Meng-Jun Liu, Jian-Cai Zhang, Ji Zhao, Jin-Song Yu
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ABSTRACT A retrospective analysis was conducted on the diagnostic and therapeutic processes of a case involving an intraspinal epidermoid cyst, with a three-year postoperative follow-up. The patient's initial symptom was fever, which was later accompanied by headache, back pain, lower extremity ...
By Jiaming Lei, Ling Wu
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ABSTRACT A middle-aged woman with acute myeloid leukaemia (M3) developed abdominal pain and haematochezia after using the Realgar- Indigo Naturalis formula (RIF). After comprehensive evaluations including enhanced CT, colonoscopy, and pathological biopsy, other diseases were excluded, and medicine-r...
By Arshad Khushdil, Andleeb Tariq, Yusra Zia, Azra Ehsan, Muhammad Amir Majeed
Page #: 37-39
ABSTRACT Organophosphates (OP) are used worldwide as insecticides and are a common cause of poisoning, particularly in developing countries. OP poisoning is potentially fatal if not recognised and treated early. It manifests as cholinergic toxicity. Reportedly, accidental poisoning is rare in neonat...
By Junaid Ul Hassan, Waris Khan, Sundus Saba, Muhammad Adnan Shakeel
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ABSTRACT The failure of the lateral lingual swellings to form between the fourth and eighth week of development results in aglossia. Other congenital abnormalities frequently coexist with it. A case of a 20-month infant girl with the complaint of not having a tongue since birth presented to the plas...
By Mehreen Shahid, Mohammad Zeeshan
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ABSTRACT Enterobius vermicularis (EV) is an intestinal parasite that usually presents with nocturnal perianal pruritis. Few extraintestinal manifestations have also been reported in the literature. Herein, we report an EV infection in the conjunctival sac of a 14-year girl with mild ocular irritatio...
By Sumeyra Emine Boluk, Akin Kocaoluk, Salih Boluk, Cagri Bilgic
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ABSTRACT Obesity is a global health problem with increasing prevalence. Its treatment is very important due to associated morbidity and mortality. Obesity surgery gives satisfactory results with high success rates. However, a less invasive method such as gastric balloon may be preferred in patients ...
By Afrah Malik, Ammarah Saeed, Sohaib Ahmad
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ABSTRACT An early sign of neurotoxic snakebite envenomation is abdominal pain. We present a 14-year boy from a rural area who was admitted with acute abdominal pain, occurring from midnight to early morning, followed by neuroparalytic symptoms. After ruling out other causes, the boy was diagnosed wi...
By Muhsin Eraslan, Ceren Turkoglu, Esra Biberoglu
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ABSTRACT The GAPO syndrome is a rare congenital disease that includes growth retardation (G), alopecia (A), pseudo-anodontia (P), and progressive optic atrophy (O). Glaucoma is a well-known disorder reported in GAPO cases. A 36-year woman, a previously diagnosed case of GAPO syndrome, has been follo...
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ABSTRACT The study investigated chronic central serous chorioretinopathy (CSCR) patients who were observed and treated between February 2023 and 2024. It is a prospective, observational case series. Three patients diagnosed with chronic CSCR, aged between 38 and 64 years, were included in the study....
By Shahzeb Saeed, Shanza Faridi
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ABSTRACT Isolated gastric Crohn’s disease is a rare and often under-recognised condition. We report the case of a 34-year male who presented with epigastric pain, nausea, early satiety, and significant weight loss. Routine investigations, including imaging and laboratory studies, were inconclu...